A New Quassinoid from Crude Quassin-extract of Quassia amara Article. Quassinoids from Picrasma Crenata Journal of Asian Natural Products Research. A new quassinoid, 2-dihydroailanthone, has been isolated from the bark of Ailanthus glandulosa. Its structure was established on the basis of spectroscopic data. ISSN: Online Available at International Journal of Herbal Medicine. Quassinoids and Their Chemotaxonomic Significance.

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If you are not the author of this article and you wish to joyrnal material from it in a third party non-RSC publication you must formally request permission using Copyright Clearance Center. In vitro antitrypanosomal activities of quassinoid compounds from the fruits of a medicinal plant, Brucea javanica. Journal of the Chemical Society, Perkin Transactions 1. Search articles by author Tony K. Authors contributing to RSC publications journal articles, books or book chapters do not need to formally request permission to reproduce material contained in this article provided that the correct acknowledgement is given with the reproduced material.

Quassinoids with dock scores Click here to view. In silico evaluation for the potential naturally available quassiniod for breast cancer. Reproduced material should be attributed as follows: Go to our Instructions for using Copyright Clearance Center page for details. Back to tab navigation Fetching data from CrossRef.


In vitro antimalarial activity of quassinoie from Eurycoma longifolia against Malaysian chloroquine-resistant Plasmodium falciparum isolates. Int J Parasitol ; Jump to main content. Mol Biochem Parasitol ; A well known plant product, quassinoids are known to have antimalarial activity. Biologically active quassinoids and their chemistry: Int J Comput Appl ; If you are the author of this article you do not need to formally request permission to reproduce figures, diagrams etc.

The ligands used for the study are the quassinoids. You do not have JavaScript enabled. For reproduction of material from PCCP: This may take some time to load. The dock results conclude that the quassinoids can be adopted as an alternative drug against malaria. For reproduction of material from PPS: How to cite this article: Kinetic properties of dihydrofolate reductase from wild-type and mutant Plasmodium vivax expressed in Escherichia coli.

Plant products as antimicrobial agents. Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target. Structural requirements of quassinoids for the inhibition of cell transformation.

Please enable JavaScript to access the full features of the site or access our non-JavaScript page. If you are the author of journao article you still need to obtain permission to reproduce the whole article in a third party publication with the exception of reproduction of the whole article in a thesis or dissertation. Antimalarial activity of simalikalactone E, a new quassinoid from Quassia amara L.

Malaria is an infection caused by mosquitoes in human beings which can be dangerous if untreated. Active site identification with pocket information Click here to view.


A new antimalarial quassinoid from Simaba orinocensis.

Open J Synth Theory Appl ;2: Search Pubmed for Rampogu S. Nucleic Acids Res ; The present study proves the promising potential of quassinoids as novel drugs against malaria. They were drawn using chemsketch and the 3D structures were generated. In all cases the Ref. For reproduction of material from NJC: The software used for the present study is the discovery studio Accelrys 2. The H-bond interactions of quassinoid 1 with active site residues of quassinoid 1 with DHFR from Plasmodium falciparum Click here to view.

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Tetracyclic quassinoid skeletons 2 and 22 with six correct chiral centres common to numerous quassinoids are constructed from S -carvone and 3-methylsulfolene by a step and step reaction sequence involving highly regioselective and stereocontrolled reactions. J Chem Ecol ; Synthesis of optically active tetracyclic quassinoid skeleton.

An in silico approach. Computed atlas of surface topography of proteins with structural and topographical mapping of functionally annotated residues. Synthesis of optically active tetracyclic quassinoid skeleton T.

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